Cell Therapy for Cancer, Autoimmune/Immuno Deficiency Disorders

ProGenaCell physicians encourage patients to undergo a thorough diagnosis before commencing cell therapy. For many patients live with misdiagnosed diseases and/or illnesses for years, never knowing why they are sick. Moreover, many patients take prescriptions drugs designed to treat the symptom(s), not NECESSARILY the causations, often resulting in some drugs actually preventing the patient from ever achieving optimal health.

Diagnostic Objectives:

1. Determine what most influences the body's malfunction, including any disease processes either pronounced or subtle. This requires a complete review of the patient's medical history, along with prior or contemporary exams and tests. Often medical exams overlook or dismiss such tests as: heavy metals, GI tract problems (such as infections that produce endotoxins that wind up in the patient's circulation), oxygen levels during sleep, genetic factors, and nutritional, dietary, and lifestyle influences, along with vitamins, herbs, and herbal compounds, taken on a regular basis.
2. To take what is revealed in the patient's medical history and various exams to formulate a targeted, personalized treatment plan. This includes dealing with excess heavy metals if present, restoring insulin sensitivity, substituting harsh drugs with gentle natural compounds when possible, addressing hormone imbalances or deficiencies and infections (including subtle or smoldering ones), plus introducing specific nutritional dietary, supplements, and lifestyle measures aimed at slowing or even halting progression of the disease.

Most cell therapy patients are middle-aged or older, with a reservoir stem cells in their bone marrow, but of senescent (inactive) cells. Senescent stem cells can no longer divide and multiply, thus becoming nearly useless in healing the body. In fact they have been known to cause inflammation in older persons, which can aggravate heart and circulatory problems.

Therefore, our physicians often use FDA approved injections of a stem cell mobilizing drug to purge these devitalized stem cells and in turn help the body to produce larger numbers of healthy, robust replacement cells. Based upon a number of circumstances, our physicians would ultimately select which source of stem cells (or perhaps a combination) that would be best for the patient's overall treatment.

Making Sure the Diagnosis is Correct:

When first see by your doctor, you should provide them with your medical records as part of the gathering information phase, which in combination with taking a medical history and doing relevant exams and tests, helps with the new diagnosis (or confirm previously made ones) and formulation of a medical care plan. Our physicians do this intensive review to ferret out previously undetected causes and contributors to the patient's health problems.

Correct Testing & Other Assessments:

Heavy metals - such as mercury, lead, cadmium, arsenic, etc. With adults, a DMPS Challenge test may be undertaken where the patient receives 250 mgs of DMPS in 250 milliliters saline via intravenous drip over a 2-hour period. The patient's urine is collected 2-6 hours and sent to Doctor's Data in Chicago for analysis, which helps determine the presence & levels of toxic and essential elements.

Hormone Deficiencies/Excesses - hyperthyroidism, hyperthyroidism, etc. Excessive hormones or the absence of certain hormones can impact stem cells, as well as the tissues they engraft (hormones can affect tissue changes that can dampen or otherwise impede stem cell activity). Where indicated, our physicians will order hormone panel tests that measure such hormones as DHEA, IGF-1, HGH, estrogen, progesterone, testosterone and prolactin.

Insulin Resistance – when the body produces insulin that is not used effectively, glucose builds up in the blood instead of absorbed by the cells, leading to type 2 diabetes or pre-diabetes. Most people with insulin resistance don't know they have it for many years until it develops into type 2 diabetes, which is a serious, lifelong disease.

Physical Stressors - including but not limited to hypoxia (low blood and tissue oxygen levels), intermittent hypoxia, nocturnal hypoxemia (serious drops in tissue oxygen levels), chronic persistent hypoxia secondary to COPD (emphysema), metabolic acidosis (happens in poorly controlled diabetes) or other noxious tissue conditions. To detect & measure the extent of issues, physicians order tests that measure CO2 blood levels, LDH enzymes, lactic acid, pyruvic acid levels, salivary and urine pH. Patients often undergoing an oximetry test, EKG, and pulmonary function studies as well.

Infections - our physicians may look for active infections whether bacterial, viral, or mycoplasma in nature - in gums, sinuses, organs or other tissues, plus smoldering or hard-to-detect low grade infections, especially those caused by certain herpes viruses and retroviruses. Among the tests our physicians consider when indicated are CT of the lungs & sinuses to rule out sinus infections, a CDSA plus parasite test to rule out intestinal infestations as these types of infections tend to attract stem cells, including those that would ordinarily wind up supporting the body's homeostasis.

Nutritional Status & Issues - Poor nutrition, ingestion of unhealthy fats and simple sugars, binge or heavy drinking, consumption of carbonated beverages especially sugar-laden ones, overconsumption of caffeine, etc. can complicate the health of patients. In addition, the lack of certain nutrients, especially vitamin D deficiency and excess amounts of others, such as vitamins K and A, can all impede or interfere with stem cells. Generally, our physicians do a systematic review of a patient's diet, which may require the patient to keep a food diary for a period of time. (Sometimes specialized testing is done to see if nutritional deficiencies or excesses exist.)

Review of Prescription and/or OTC Pharmaceuticals - Drug interactions and excessive or wrong drug choices can have adverse effects on stem cell growth, proliferation or function. Physician's review each patient's past & present drug & supplement use (or has the patient do this with their family doctor) to determine what might be contributing to the SPA disease process or its symptoms, OR are unfriendly to stem cells.

Review of Herbs, Herb-derived Compounds, and Vitamins - Many herbs, herbal concentrates/extracts and vitamins can negatively impact certain illnesses, as well as influence stem cell growth, proliferation or function. Patients are asked to provide our physicians with detailed list or record of all their herbs, herbal formulas, teas, vitamins, etc.

Assessing Influences of Current & Future Genetics - our physicians makes use of various highly sophisticated tests to help gauge such things as: (1) how a patient is likely to respond to (a) particular medication(s) our physicians feel the patient may benefit from using; and (2) their risk of developing specific chronic diseases in the future. One comprehensive genetics test our physicians may have a patient undertake is "23andme". This kind of testing makes it possible to personalize many aspects of the care provided.

Additional Testing:

CBC, ESR, CRP thyroid panel, uric acid, ammonia (brain cases), EPO, if anemia is present, reticulocyte count, iron, TIBC, % saturation, copper, ceruloplasmin, ANA with reflex, and urine organic acids. For patients with strokes an antiphospholipid panel and alpha 2 macroglobulin test. If vasculitis is present or suspected a haptoglobin assay is generally ordered. If patient is presented with congestive heart failure, the brain-natriuretic peptide, fibrinogen and d-dimer tests are considered.

Charting a Personalized Treatment Course:

Once a patient's diagnosis is confirmed, modified, or even overturned, an overall treatment plan is formulated. The therapeutic regimens introduced by the Drs. are personalized to help ensure the patient receives their optimal results and has the greatest shot at making significant clinical improvements.

• If heavy metals toxicity is present then a course of chelation therapy is typically prescribed.
• Hormone corrections
• Infections eradication
• Nutritional deficiencies and unique dietary needs are addressed. This may entail prescribing individualized therapeutic diet and possibly oral or IV nutritional therapies.
• If patients use prescribed and/or OTC drugs, our physicians may well substitute gentle but equally effective natural compounds when possible. If drugs are essential, then they will confirm there are no potential conflicts or interactions between these and any herbs, herbal compounds, or vitamins the patient routinely takes.